Over the course of a career that stretches back nearly 40 years, comedian Paula Poundstone has been a regular guest on several NPR programs and has performed for the likes of Hillary Clinton and Johnny Carson. In her books, including There Is Nothing in This Book That I Meant to Say and The Totally Unscientific Study of the Search for Human Happiness, she provides a humorous look at life and zeroes in on the never-ending quest for happiness. Expect Poundstone to improvise plenty at tonight's show, which takes place at 8 at the Ohio Theatre. Tickets start at $10. (Niesel)